The FDA approved daraxonrasib, a new pill for advanced pancreatic cancer, one of the hardest cancers to treat. In its trial, half the patients taking it were still alive at 13 months, compared with under 7 months on standard chemo. Some lived for years.

The drug is two pills a day, taken at home. It works by blocking RAS, the mutation that drives most pancreatic tumors.

It costs hundreds of thousands of dollars a year. But for a cancer this hard to treat, doubling survival is real progress.

A study on fluoride and pregnancy is drawing fresh attention. Researchers tracked pregnant women, then tested their children years later. The kids exposed to more fluoride in the womb scored a little lower on IQ tests, mostly on reasoning. A recent federal review found the same pattern: more fluoride, lower scores.

In April 2025, RFK Jr. directed the CDC to stop recommending fluoride in drinking water, and HHS and the EPA opened a review. Utah became the first state to ban it outright, and Florida followed. The one effort to force the EPA's hand has since stalled: a 2024 court order requiring the agency to regulate fluoride was thrown out on appeal in May 2026 and sent back to a lower court. For now, nothing is settled.

TOGETHER WITH PENDULUM

Did you hear about the group of PhD scientists from Johns Hopkins, Harvard, and Stanford who walked into a lab—and left with a breakthrough probiotic in hand? These scientists zeroed in on one of the most beneficial strains for gut health, Akkermansia muciniphila. They figured out how to bring live Akkermansia muciniphila to the probiotics market. The final result of their work? Pendulum's Metabolic Daily probiotic.

This particular strain is so groundbreaking because it can strengthen gut lining, improve metabolic and digestive health, and support natural GLP-1 signaling pathways.* With more than 15k medical provider recommendations, 4.5k mentions of Akkermansia muciniphila in scientific publications, and loyal customers like Halle Berry, this stuff sure sounds promising. HSA/FSA eligible.

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A decades-long study of American men found testosterone dropping about 1% a year, so the average man now measures lower than a man his age did a generation ago. Sperm counts fell alongside it: down about 50% among Western men between 1973 and 2011.

The measured drivers are weight, sleep, and chemical exposure. In one experiment, cutting men's sleep to five hours a night for a week lowered their testosterone 10 to 15%. Men with the most exposure to the chemicals that leach out of plastic food packaging also show lower testosterone in national data. What reliably pushes it back up is dull: lose excess weight, lift, and sleep enough.

A story is going around online: that the US just cut tariffs to buy the beef China rejected as poisoned. Here is what is actually true.

In March, China turned back a 22-ton shipment of Argentine beef after inspectors found chloramphenicol, an antibiotic banned from food animals in the US, China, and the EU. It is banned for a reason. In rare cases it triggers aplastic anemia, a fatal collapse of the body's blood supply, and even a trace can set it off in the wrong person.

Five months later, the US waived tariffs on imported beef for 90 days. The order named no country, and there is no evidence the rejected Argentine beef is headed here. But the timing is what has people talking.

TOGETHER WITH ORGANIXX

You're exhausted… but as soon as your head hits the pillow, your brain won't turn off. Or maybe you finally fall asleep… only to wake up at 2:37 AM staring at the ceiling. For millions of people over 35, the problem isn't just stress, blue light, or bad luck—it's a simple mineral deficiency.

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A 38-year-old man in China went to the doctor with two weeks of nosebleeds that would not stop. Nobody could find the cause, until they looked up his nose with a camera and found a live leech settled in against his septum, fat with blood.

He had rinsed his face in a mountain spring days earlier, and it climbed in. A leech's saliva keeps a wound bleeding while it feeds, which is why the nosebleeds never quit. Doctors pulled it out and the bleeding stopped.

The case ran in the New England Journal of Medicine. The lesson: don't rinse your nose with water you wouldn't drink.

Today's fourth story is the beef rumor. Your turn:

🟩🟩🟩🟩🟩🟩🟩⬜️⬜️⬜️ Yes (223)
🟩🟩⬜️⬜️⬜️⬜️⬜️⬜️⬜️⬜️ Unsure (51)
🟩⬜️⬜️⬜️⬜️⬜️⬜️⬜️⬜️⬜️ No (31)

A fishing guide off St. Simons Island, Georgia spotted a manatee tangled in crab-trap lines, the rope cutting into her skin, and called it in. A team from four agencies came out over two days. They meant to net her, but her calf kept swimming in close, so they freed her by hand instead, cut away the rope and the buoy, and let mother and calf swim off together. It was the first rescue of its kind in the state. Four agencies, two days, one phone call from a guy who could have just kept fishing.

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