Moderna and Merck reported that a personalized cancer vaccine cut the risk of melanoma coming back by 49% over five years. Melanoma is the deadliest form of skin cancer, and it often returns after surgery.

How it works: doctors sequence a patient's own tumor, find the mutations that make it unique, and build an mRNA shot that trains the immune system to attack cells carrying those mutations. Each vaccine is made unique for each person.

Cutting the odds of return nearly in half is real progress. The catch: it is brand new, not yet approved, and it is mRNA, from Moderna.

A sunburn is an inflammation problem. UV light damages the skin, and the body floods it with the same chemicals that drive swelling and pain, which is why the burn turns red and tender hours later. Treat the inflammation, and you treat the burn.

Here is what the research says works. Ibuprofen blocks those inflammation chemicals, so taken early it cuts the redness at the source, not just the pain. Aloe is not a myth: a review of clinical trials found it healed burns about 9 days faster, because its compounds push the skin's repair cells to rebuild. Around that, the basics: cool (not icy) water to draw the heat out, a plain moisturizer on still-damp skin to lock water in, and extra fluids, since a burn pulls water to the surface.

What we skip: butter and oils trap heat, and numbing sprays irritate raw skin. And leave the blisters alone. They are a bandage your body already made.

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I take a cold plunge after the sauna, and the jolt is real. Studies that measured it found a few minutes in cold water can raise your dopamine by about 250%, and noradrenaline even more. That is why you step out sharp and in a better mood.

Apparently though, don't plunge right after lifting. Lifting builds muscle by causing tiny tears that repair on inflammation, and cold shuts that inflammation down, quieting the signal that makes you stronger. Save it for rest days, not straight off the gym floor. The bigger claims, less stress, deeper sleep, more testosterone, still have thin evidence behind them. Enjoy the reset. Skip the hype.

Trump nominated Dr. Heidi Overton to lead the FDA. She is deputy director of the White House Domestic Policy Council and a physician trained in preventive medicine, with a PhD from Johns Hopkins. Working alongside RFK Jr., she has been a public face of the administration's health agenda: she stood with Trump to announce the "most favored nation" deals meant to cut drug prices, and again on the order splitting the childhood MMR shot into three separate injections. She is also a critic of the abortion pill.

The seat opened when Commissioner Marty Makary resigned in May, leaving the fights over ultra-processed food and additives unfinished. Overton still needs Senate confirmation, and her hearing runs through Senator Bill Cassidy, a Republican doctor who has broken with the administration over vaccine skepticism, so it is not a lock. If she gets in, the agency that decides what goes on your food label and which additives are allowed would be run by one of the people trying to change those rules, not defend them.

If your car insurance policy is about to expire, this is the moment to check whether you're still getting the best deal. Compare.com pulls real-time quotes from more than 120 top insurers — no cold calls, no repeat forms. Just share your info once and see personalized rates side by side in minutes. Compare.com customers have saved up to $900 a year*. Renewal is the easiest time to switch, and it's free to look. See your options before your policy locks back in.

A 65-year-old woman celebrated at her daughter's wedding, went home glowing, and three days later landed in the ER with chest pain and trouble breathing. Doctors thought it was a heart attack. There was no blockage. Her heart's main pumping chamber had ballooned out of shape, choking its own blood flow. The cause was not a clogged artery. It was pure joy. Doctors call it broken heart syndrome, usually set off by grief, but a small share of cases are triggered by happiness instead. She made a full recovery. The wedding, by all accounts, was worth it.

After you vote, there's a box. Tell us why, we read every one.

🟩🟩🟩🟩🟩🟩🟩🟩🟩🟩 Good, but the loophole guts it (83)
🟩🟩🟩🟩🟩🟩🟩🟩🟩⬜️ Too slow, this should have happened years ago (74)
🟩🟩🟩🟩🟩🟩🟩🟩⬜️⬜️ A real win, finally (63)
🟩🟩🟩🟩⬜️⬜️⬜️⬜️⬜️⬜️ Fine, now hold whoever funded it accountable (35)
🟩⬜️⬜️⬜️⬜️⬜️⬜️⬜️⬜️⬜️ I won't trust it until the full COVID origin is out (6)

Mabel Rose was born with half a heart. At seven months old, the baby from Lake Worth Beach, Florida got a heart transplant, and it nearly did not hold: her heart stopped on the table when the new valve leaked, and a machine kept her blood moving until the surgeons could fix it. She pulled through. She is home now. Her mother calls the donor family "a beautiful faithful village." One family's hardest day gave another family every day still to come.