The FDA just approved a gene therapy for Sanfilippo syndrome type A, a rare disease that steals a child's mind before age 10.

Children with it are born missing one cleanup enzyme. That enzyme clears a sugary waste from brain cells. Without it, the waste builds up until the cells die, usually by the mid-teens. Fayuvi, the new therapy, is a single IV infusion that gives cells a working copy of the missing gene, so they make the enzyme themselves.

In the trial, treated kids held on to far more of their thinking than children with this disease normally do. Until this week, these families had nothing.

Berkeley became the first US city to ban candy and sugary snacks from store checkout lines, and researchers tracked what changed.

Across 71 stores, sugar sold at the register dropped about 70% in the first year. Soda and small candy packs fell in supermarkets. Drug stores did not change at all. But total candy sales across the city rose slightly over the same period. Interesting, though: people seem to have just gotten their fix elsewhere in the store, and a little more of it overall.

Move the candy, and the craving just finds another aisle.

TOGETHER WITH ALLEGIANCE GOLD

Federal debt crossed $40 trillion, and interest now runs near $1 trillion a year. What could it mean for your savings?

In a new randomized trial, adults with obesity and prediabetes were split into two groups for 12 weeks.

One ate all their food inside a 10-hour window. The other ate on a normal schedule. Both groups ate the same number of calories. Both lost about the same amount of weight, roughly 2.5%. Hunger, blood sugar hormones, and inflammation came out about even too.

The fasting window itself did nothing extra.

Pennsylvania has now tied four deaths this year to its measles outbreak, including an 18-year-old and a 40-year-old woman.

RFK Jr.'s health department says the national measles death toll for 2026 is zero. Both cannot be true. Pennsylvania keeps counting cases, now more than 700 across 38 counties, and keeps counting bodies. Kennedy keeps insisting measles may not be what killed them.

Neither side is blinking. This week, Pennsylvania escalated, asking the CDC to step in and settle it.

TOGETHER WITH PENDULUM

Did you hear about the group of PhD scientists from Johns Hopkins, Harvard, and Stanford who walked into a lab—and left with a breakthrough probiotic in hand? These scientists zeroed in on one of the most beneficial strains for gut health, Akkermansia muciniphila. They figured out how to bring live Akkermansia muciniphila to the probiotics market. The final result of their work? Pendulum's Metabolic Daily probiotic.

This particular strain is so groundbreaking because it can strengthen gut lining, improve metabolic and digestive health, and support natural GLP-1 signaling pathways.*

With more than 15k medical provider recommendations, 4.5k mentions of Akkermansia muciniphila in scientific publications, and loyal customers like Halle Berry, this stuff sure sounds promising.

HSA/FSA eligible.

Based on preclinical studies. This product is not intended for weight loss

Here is a reason to read the label on your hair dye.

A 61-year-old man in India colored his hair, felt a little itching, and thought nothing of it. Two days later he fainted twice and collapsed, his face swelling and his blood pressure crashing, in what doctors judged a likely anaphylactic reaction to the dye. The suspected trigger was PPD, or para-phenylenediamine, the main coloring chemical in most permanent dyes. His immune system had reacted to it on a strange delay, and time in the sun may have made it worse. It took many hours of IV epinephrine to stabilize him, and about a week in the hospital before he went home.

The label warns you to patch-test first. This is why.

🟩🟩🟩🟩🟩🟩🟩🟩🟩🟩 Yes (122)
🟩⬜️⬜️⬜️⬜️⬜️⬜️⬜️⬜️⬜️ Not sure (11)
🟩⬜️⬜️⬜️⬜️⬜️⬜️⬜️⬜️⬜️ No (6)

A construction worker from Chicago lost his left arm above the elbow in 2016. This summer, he took the first real step toward getting it back.

He became the first person in the US to receive a new bionic-arm system anchored straight into his bone and wired into the nerves and muscles of his upper arm. The surgery is done, and his muscle signals are already coming through. Over the months of rehab ahead, the goal is for him to move the hand just by thinking about it, and one day to feel what it touches, the hardest problem prosthetics have never solved.

Doctors spent decades chasing a solid anchor, mind control, and real feeling as three separate problems. He is the first American wired for all three at once.

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